EVALUATION OF PHENOLIC CONTENT AND BIOLOGICAL ACTIVITIES OF BUNIUM MAURITANICUM TUBERSS
DOI:
https://doi.org/10.4314/jfas.v12i2.27Keywords:
Bunium mauritanicum, phytochemical screening, polyphenols, flavonoids, antioxidant, antibacterial activityAbstract
The present work is carried out to evaluate biological activities of tubers extracts of Bunium mauritanicum. The methanol extract yield had higher (7.81%) than that of the aqueous extract (6.79%). The quantitative analysis of total phenols and flavonoid revealed that the highest concentration was recorded for the methanoic fraction with 89,442 ± 5,951μg EAG/mg and 4.031 ± 0.141 μg EQ/mg of extract respectively. In addition, the aqueous extract of tubers represents the most important antioxidant activity with an IC50 of 0.14 mg/ml against 2,2-diphenyl-1-picryl-hydrazyl (DPPH). Whereas, the two extracts of the tubers have low reducing capacities compared to standard with EC50 equal to 0.048 mg/ml for the methanolic extract, 0.018 mg/ml for the aqueous extract and 0.009 mg/ml for ascorbic acid. The methanolic and aqueous extracts of Bunium mauritanicum reacted positively at least on one of the bacterial strains studied.
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References
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[2] Lee KH. Current developments in the discovery and design of new drug candidates from plant natural product lead. Journal of Natural Products, 2004, (67), 273-283.
[3] Sato F, Hashimoto T, Hachiya A, Tamura KI, Choi KB, Morishige T, Fujimoto H, and
Yamada Y. Metabolic engineering of plant alkaloid biosynthesis. Proc. Natl. Acad.Sci. USA, 2001, 98, (1), 367-372.
[4] Khoudali S, Benmessaoud left D, Essaqui A, Zertoubi M, Azzi M, Ben Aïssa M. Étude de l’activité antioxydante et de l’action anti corrosion de l’extrait méthanoïque des feuilles du palmier nain (Chamaerops humilis L.) du Maroc. J. Mater. Environ. Sci, 2014, 5, (3), 887-898.
[5] Duraffourd C, Lapraz JC, et Chemli R. La plante médicinale de la tradition à la science. 1er congrès Intercontinental. Tunis. Ed. Granche. Paris,1997, p. 222- 224.
[6] Trabut L. et Marès R. L’Algérie Agricole, 1906.
[7] Mohammedi Z, 2013 : Etude phytochimique et activité biologique de quelque plante médicinale de la région nord et sud –ouest de l’Algérie. Thèse de doctorat. Université de Tlemcen. 44 P.
[8] Zellagui A, Said NL, Gherraf N, Rhouati S. Phytochemical screening of five Algerian plants and the assessment of the antibacterial activity of two Euphorbia guyoniana extracts. Der Pharmacia Lettre, 2012, 4,(5), 1438-1444.
[9] Thiaw C, Emile VC, Saliou D, Mbaye D, Ousmane N, Ndiaga C, Mbacké S, Senna occidentalis L. Une plante prometteuse dans la lutte contre Caryedon serratus OI. (Coleoptera, Bruchidae), insecte ravageur des stocks d’arachides au Senegal., 2015, 9, (3), 1401-1405.
[10] Khettaf A, Belloula N, Dridi S. Antioxidant activity, phenolic and flavonoid contents of some wild medicinal plants in southeastern Algeria. African Journal Biotechnology, 2016,
15, (13), 524-530.
[11] Singleton V L, Rossi J R. Colorimetry of total phenolics with phosphomolybdic - phosphothungstic acid. Am. J. Enol.Vitic, 1965, (16), 144−158.
[12] Djeridane A, Yous M, Nadjemi B, Boutassouna D, Stocker P, Vidal N. Antioxidant activity of some Algerian medicinal plants extracts containing phenolic compounds. Food Chemistry, 2006, (97), 654-660.
[13] Brand-Williams W, Cuvelier M E, Berset C. 1995: Use of a free radical method to evaluate antioxidant activity. Lebensmittel- Wissenschaft and Technologie.
[14] Oyaizu M. Studies on products of browning reaction prepared from glucosamine. Jpn J of Nutr, 1986, 44 (1), 307–15.
[15] Karagôzler A, Erdag C S, Çalmaz Emek Y. Antioxydant activity and proline content of leaf extracts from Dorystoechas hastate. Food Chem, 2008, (111), 400–407.
[16] Seid M, Abossie A, 2014: Assessement of the prevalence of intestinal parasitosis and associated risk factors among primary school children in chencha town, Southern Ethiopia. Publichealth. Biomedcentral.com
[17] Gabrieli CN, Kefalas PG, Kokkalou EL. Antioxidant activity of flavonoids from Sideritis raeseri. Journal of Ethnopharmacology, 2005, (96), 423–428.
[18] Quy Diem D, Artik E, Angkawijayaa P, Lan T, Huong H. Effect of extraction solvent on total phenol content, total flavonoid content, and antioxidant activity of Limnophila aromatica. Journal of Food and Drug Analysis, 2014, 22 (3), 296-302.
[19] Stalikas C D. Extraction, separation, and detection methods for phenolic acids and flavonoids Review. J. Sep. Sci, 2007, (30), 3268 – 3295.
[20] Atmani D. Antioxidant capacity and phenol content of selected Algerian medicinal plants. Food Chem, 2009, (112), 303–309.
[21] Apak R, Güçlü K, Demirata B, Özyürek M, Çelik SE, Burcu Bektaşoğlu, B, Berker K I, Özyurt D. Comparative Evaluation of Various Total Antioxidant Capacity Assays Applied to Phenolic Compounds with the CUPRAC Assay. Molecules,2007, (12), 1496-1547.
[22] Bano MJ, Lorente J, Castillo J, Benavente-Garcia O, Rio JA, Otuno A, Quirin KW, Gerard D. Food Chem, 2003, (51), 42-47.
[23] Falleh H, Ksouri R, Chaieb K, Karray-Bouraoui N, Trabelsi N, Boulaaba M, Abdelly C. Phenolic composition of Cynara cardunculus L. organs and their biological activities. Comptes Rendus Biologies, 2008, 331, (5), 331- 372.
[24] Ksouri R, Megdiche W, Falleh H, Trabelsi N, Boulaaba M, Smaoui A, Abdelly C. Influence of biological, environmental and technical factors on phenolic content and antioxidant activities of Tunisian halophytes. C. R. Biol, 2008, 331, 865- 873.
[25] Molyneux A, Richard K. the International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. Journal of Stroke and Cerebrovascular Diseases, 2002, 11, (6), 304-314.
[26] Belhadj Tahar S., Hadj-Mahammed M. et Yousfi M. Etude de l’activité antioxydante des extraits phénoliques de l’Atriplex halimus L et de l’Haloxylon scoparium pomel du Sahara septentrional. Annales des Sciences et Technologie, 2015, 7, (1), 35-42.
[27] Bouzid W, Yahiai M, Abdeddaim M, Aberkane MC, Ayachi A. Evaluation de l’activité antioxydante et antimicrobienne des extraits de l’aubepine monogyne. Leban Scien, 2011, 12, 1-8.
[28] Bougandoura N, Bendimerad N. Evaluation de l'activité antioxydante des extraits aqueux et méthanolique de Satureja calamintha ssp. Nepeta (L.). Briq. Nature & Technology, 2013, 9, 14- 15.
[29] Ferreira V, Jona B, Jona S, Sandra V, Ana M, Fatima S, Mara JM, Tim H, Paula T. Chemical and microbiological characterisation of “Salpicão de Vinhais” and “Chouriça de Vinhais”: Traditional dry sausages produced in the North of Portugal. Science Direct, 2007, 24, 618-623.
[30] Prosper-Cabral N B, Gabriel A A, Julius E O, Jeanne Y N. Phytochemical studies and antioxidant properties of four medicinal plants used in Cameroon. Afr. J. Trad. CAM, 2007, 4, (4), 495 – 500.
[31] Marfak A. 2003 : Radiolyse gamma des flavonoïdes : étude de leur réactivité avec les radicaux issus des alcools : formation de depsides ; Thèse de doctorat de l’université de Limoges.
[32] Karou D, Aly S, Antonella C, Saydou Y, Carla M, Jacques S, Vittorio C, Alfred S. Antibacterial activity of alkaloids from Sida acuta. African Journal of Biotechnology, 2005, 4(12), 1452-1457.
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Published
2020-04-30
How to Cite
KAROUCHE, S.; BENBOTT, A.; HENOUDA, S.; MALKI, S.; BOUDCHICHA, I. EVALUATION OF PHENOLIC CONTENT AND BIOLOGICAL ACTIVITIES OF BUNIUM MAURITANICUM TUBERSS. Journal of Fundamental and Applied Sciences, [S. l.], v. 12, n. 2, p. 916–930, 2020. DOI: 10.4314/jfas.v12i2.27. Disponível em: https://jfas.info/index.php/JFAS/article/view/789. Acesso em: 1 apr. 2023.
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