THE ENDEMIC MEDICINAL SPECIE WARIONIA SAHARAE ( ASTERACEAE): A PROMISING SOURCE OF BIOACTIVE NATURAL COMPOUNDS
DOI:
https://doi.org/10.4314/jfas.v12i1S.11Keywords:
Endemic, Warionia saharae, Asteraceae;, Ethnopharmacological, Biological activities, Phytochemical, SaharaAbstract
Algeria with its large area and diversified climate has a varied flora, which is a source of rich and abundant medical matter and, in particular Sahara part constitutes an important reservoir of many plants which have not been investigated until today. Among this flora, species from Asteraceae family has been used in the local traditional ethnopharmacopeae.
The aim of this review is to present as much information as was established from the available scientific literature, on the ethnopharmacological, biological activities and phytochemical of the endemic medicinal specie from Algerian Sahara namely: Warionia saharae (Asteraceae family).
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References
[1] Cheriti, A. (under press 2020). Endemic Asteraceae from Algerian Sahara: Potential Medicinal Value and Chemical Diversities, in Asteraceae: Characteristics, Distribution and Ecology; edited by Millicent Tessier, Chapter III Nova Science Publishers, New York, USA.
[2] Ibn al-Baytar, Dhiya al-Din. (1992). Kitāb al-jāmiʿ li-mufradāt aladwiya wa al-aghdhiya [Compendium on Simple Medicaments and Foods], Ed. Dar Kotob Elmia, Libanon.
[3] Bellakhdar, J. (1997). La pharmacopée marocaine traditionnelle. Médecine arabe ancienne et savoirs populaires [Moroccan traditional pharmacopoeia. Ancient Arabic medicine and popular knowledge], IBIS Press.
[4] Cheriti, A. (2019). Limoniastrum feei from the Algerian Sahara: Ethnopharmacology, Phytochemistry and the Pharmacological Importance, in Plant sources and potential health benefits, edited by Iman Ryan, 259-299, Nova Science Publishers, New York, USA.
[5] Cheriti, A., Belboukhari, M., Belboukhari, N. and Djeradi; H. (2012). “Phytochemical and biological studies on Launaea Cass. Genus (Asteraceae) from Algerian Sahara”Current Topics in Phytochem 11, 67-80.
[6] Rodríguez Villanueva, J., Esteban, J. M. and Rodríguez Villanueva, L. (2018). “Pharmacological Activities of Phytomedicines: A Challenge Horizon for Rational Knowledge” Challenges 9, 15-22.
[7] Gurib-Fakim, A. (2006). Traditions of yesterday and drugs of tomorrow. Molecular Aspects of Medicine. Special Edition, Elsevier Publications, UK.
[8] Wiart C. (2006). Medicinal plants of the Asia-pacific drugs for the future, World Scientific Publishing Co., Singapore
[9] Dobignard, A. and Chatelain, C. (2013). Index synonymique de la flore d’afrique du nord [Synonymic index of the flora of North Africa], Editions des conservatoire et jardin botaniques, Genève.
[10] Ozenda, P. (2004). Flore et Végétation du Sahara [Flora and vegetation of the Sahara], CNRS, Paris
[11] Cheriti, A. (2000). Medicinal Plants of the Bechar Region, Ethnopharmacologie studies, CRSTRA Report, Algeria.
[12] Vicki A. F., Alfonso S., Tod F. S. and Randall B. (2009). Systematics, Evolution, and Biogeography of Compositae, IAPT, Vienna, Austria
[13] Katinas, L., Tellería, M.C., Susanna, A. and Ortiz, S. (2008) “Warionia (Asteraceae): a relict genus of Cichorieae?” Anales del Jardín Botánico de Madrid 65(2), 367-381.
[14] Audissou, J.A. (1999) “Warionia saharae” Brit. Cactus and Succulent J. 17(3), 124-126.
[15] Bremer, K. (1994) Asteraceae: Cladistics and classification. Timber Press, Portland, Oregon.
[16] Wannes,W. A. and Marzouk, B. ( 2016) “Research progress of Tunisian medicinal plants used for acute diabetes” J. Acute Disease 5(5), 357–363
[17] Cox, P.A. and Balick M.J. (1994) “The ethnobotanical approach to drug discovery” Scientific American 270(6), 82–87.
[18] World Health Organization (WHO) (2000) General guidelines for methodologies on research and evaluation of traditional medicine, WHO, Geneva
[19] Cheriti, A., Rouissat, A., Sekkoum, K. and Balansard, G. (1995) "Plantes de la pharmacopée traditionelle dans la région d'El-Bayadh (Algérie)" Fitoterapia 66 (6), 525-538.
[20] Cheriti, A., Belboukhari, N. and Hacini, S. (2013). “ Ethnopharmacological survey and phytochemical screening of some medicinal Asteraceae from Algerian Sahara” Phytochem & BioSub J. 7 (2), 52-56.
[21] Cheriti, A. (2018). “Phytochemistry and biological activities of some endemic Saharan medicinal plants” Paper presented at the International Days of Organic Chemistry, Annaba, December 3-5.
[22] Watillon, C., Gaspar, T., Hofinger, M. and Ramaut, J.L. (1987) “La micropropagationde Warionia saharae Benth. & Coss.” Al Biruniya 4: 35-38.
[23] Berbaoui, H., Cheriti, A. and Ould El Hadj-Khelil, A. (2018) "Antibacterial Effect of Some Asteraceae of Southern Algeria on Nosocomial Strains of the Genus Staphylococcus" Nat Prod Chem Res 5: 302. doi:10.4172/2329-6836.1000302
[24] Rouissat, L. (2017). Etude des effets nématicides et molluscicides des extraits de quelques plantes sahariennes, Doctorat Diss., UAB-Oran 1
[25] Cheriti, A., Belboukhari, N., Bombarda, I. and Gaydou, E. (2010) “Antimicrobial Activity and Chemical Composition of the Essential Oil from the Sahara Endemic Medecinal Plant Warionia saharae (Asteraceae)” Rev. Regions Arides, 23(1), 103-107.
[26] (a) Belboukhari, M., Cheriti, A. and Belboukhri, N. (2011) “Total phenolic content and in vitro antioxydant activity of extracts from the endemic medicinal plant Warionia saharae” Nat. Prod.Ind. J., 7(3), 147-150. (b) Keffous, F., Belboukhari, N., Djeradi, H., N.M.Rebizi, Cheriti, A., Sekkoum, K. and Aboul-Enein, H. Y. (2019) “Optimization of the reducing power for antioxidant activity test and application on two medicinal plants” PhytoChem & BioSub J. 13(2), 81-85
[27] Znini, M., Cristofari, G., Majidi, L., El Harrak, A., Paolini, J. and Costa, J. (2013) “In vitro antifungal activity and chemical composition of Warionia saharae essential oil against 3 apple phytopathogenic fungi” Food Sci. Biotechnol. 22(S1), 113-119.
[28] Amezouar, F., Badri, W., Hsaine, M., Bourhim, N. and Fougrach, H. (2012) Chemical Composition, Antioxidant and Antibacterial Activities of Leaves Essential Oil and Ethanolic Extract of Moroccan Warionia saharae Benth. & Coss.” J. App. Pharm. Sci., 2(5), 212-217.
[29] Amezouar, F., Badri, W., Hsaine, M., Aksim M., Bourhim, N. and Fougrach, H.(2012) “subacute toxicity, anti-inflammatory and antioxidant activities of ethanolic extract of moroccan warionia saharae from Tata region” Intern. J. Pharm. Pharm. Sci. 4(5), 528-533.
[30] Mabry, T.J. and Bohlmann, F. (1977) Summary of the chemistry of the Compositae. In: Heywood, V.H . & al. (eds.), The Biology and Chemistry of the Compositae 2, Academic Press, London.
[31] Hilmi, F., Sticher, O. and Heilmann, J. (2002) “New Cytotoxic 6,7-cis and 6,7-trans configured Guaianolides from Warionia saharae” J. Nat. Prod.,65, 523-526.
[32] Hilmi, F., Gertsch, J., Bremner, P., Volovic, S., Heinrich, M., Sticher, O. and Heilmann, J. (2003) “Cytotoxic versus Anti-inflammatory effects in HeLa, Jurkat T and Human Peripheral Blood Cells caused by Guaianolide-Type sesquiterpene lactones” Bioorg. Med. Chem. 11, 3659-3663.
[33] Buckingham J., Cooper C. M. and Purchase R. (2016). Natural Products Desk Reference; CRC Taylor & francis, NY.
[34] Si-Yuan, P., Shu-Feng, Z., Si-Hua, G., Zhi-Ling, Y., Shuo-Feng, Z., Min-Ke, T., Jian-Ning, S., Dik-Lung, Ma.,Yi-Fan,H., Wang-Fun F. and Kam-Ming, K. (2013) “New Perspectives on How to Discover Drugs from Herbal Medicines: CAM’s Outstanding Contribution to Modern Therapeutics” Evidence-Based Complementary and Alternative Medicine, DOI: 10.1155/2013/627375
[35] Bucar, F., Wube A. and Schmid, M. (2013) “Natural product isolation – how to get from biological material to pure compounds” Nat. Prod. Rep. 30, 525–545.
[36] Sarker, S.D, Latif, Z. and Gray, A.I. (2005) Natural Products Isolation, 2ed Ed., Humana Press, New Jersey.
[37] Colegate, S. M. and Molyneux, R.J. (2007) Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition, 2ed Ed., CRC Press
[38] Ramaut, J. L., Hofimger, M., Dimbi, R., Corvisier, M. and Lewalle, J. (1985) “Main Constituents of the Essential Oil of Warionia Saharae Benth and Coss.” Chromatographia 20, 193-194.
[39] Yakoubi, M., Belboukhari, N., Sekkoum, K., Cheriti, A., Bouchekara, M.and Aboul-Enein, H. Y. (2015) “The Chemical Composition of Essential Oil of Warionea saharae Benth & Coss.(Fam.Asteraceae) from Southern Algeria” Current Bioactive Compounds, 11, 116-121
[40] Hilmi, F., Sticher, O. and Heilmann, J. (2003) “New cytotoxic sesquiterpene lactones from Warionia saharae. Planta Med. 69(5), 462-464.
[41] Essaqui, A., Elamrani, A., J. A. Cayuela and Benaissa, M. (2007) " Chemical Composition of the Essential Oil of Warionia saharae from Morocco” J. Ess. Oil Bear. Plants 10(3), 241 -246.
[42] Essaqui, A., Elamrani, A., Benaissa, M., Rodrigues, A. I. and Yoongho, L. (2004) " Chemical Composition of the leaves extract of Warionia saharae of Morocco” J. Ess. Oil Bear. Plants 7(3), 250-254,
[43] Sellam, K., Ramchoun, M., Alem, C., Khallouki, F., El Moualij, B. and El Rhaffari1, L. (2012) Chemical composition antioxidant and antimicrobial activities of essential oil of warionia saharae from oases of morocco, In: Gas Chromatography – Biochemicals, Narcotics and Essential Oils; Bekir Salih, Ömür Çelikb çak, Eds.; InTech, pp. 213-220.
[44] Mezhoud, S., Derbré, S., Ameddah, S., Mekkiou, R., Boumaza, O., Seghiri, R., Benayache, S., Richomme, P. and Benayache, F. (2012) “Antioxidant Activity And Chemical Constituents Of Warionia Saharae Benth. & Coss. (Compositae) From Algeria” Int. J. Med. Arom. Plants 2(3), 509-513.
[2] Ibn al-Baytar, Dhiya al-Din. (1992). Kitāb al-jāmiʿ li-mufradāt aladwiya wa al-aghdhiya [Compendium on Simple Medicaments and Foods], Ed. Dar Kotob Elmia, Libanon.
[3] Bellakhdar, J. (1997). La pharmacopée marocaine traditionnelle. Médecine arabe ancienne et savoirs populaires [Moroccan traditional pharmacopoeia. Ancient Arabic medicine and popular knowledge], IBIS Press.
[4] Cheriti, A. (2019). Limoniastrum feei from the Algerian Sahara: Ethnopharmacology, Phytochemistry and the Pharmacological Importance, in Plant sources and potential health benefits, edited by Iman Ryan, 259-299, Nova Science Publishers, New York, USA.
[5] Cheriti, A., Belboukhari, M., Belboukhari, N. and Djeradi; H. (2012). “Phytochemical and biological studies on Launaea Cass. Genus (Asteraceae) from Algerian Sahara”Current Topics in Phytochem 11, 67-80.
[6] Rodríguez Villanueva, J., Esteban, J. M. and Rodríguez Villanueva, L. (2018). “Pharmacological Activities of Phytomedicines: A Challenge Horizon for Rational Knowledge” Challenges 9, 15-22.
[7] Gurib-Fakim, A. (2006). Traditions of yesterday and drugs of tomorrow. Molecular Aspects of Medicine. Special Edition, Elsevier Publications, UK.
[8] Wiart C. (2006). Medicinal plants of the Asia-pacific drugs for the future, World Scientific Publishing Co., Singapore
[9] Dobignard, A. and Chatelain, C. (2013). Index synonymique de la flore d’afrique du nord [Synonymic index of the flora of North Africa], Editions des conservatoire et jardin botaniques, Genève.
[10] Ozenda, P. (2004). Flore et Végétation du Sahara [Flora and vegetation of the Sahara], CNRS, Paris
[11] Cheriti, A. (2000). Medicinal Plants of the Bechar Region, Ethnopharmacologie studies, CRSTRA Report, Algeria.
[12] Vicki A. F., Alfonso S., Tod F. S. and Randall B. (2009). Systematics, Evolution, and Biogeography of Compositae, IAPT, Vienna, Austria
[13] Katinas, L., Tellería, M.C., Susanna, A. and Ortiz, S. (2008) “Warionia (Asteraceae): a relict genus of Cichorieae?” Anales del Jardín Botánico de Madrid 65(2), 367-381.
[14] Audissou, J.A. (1999) “Warionia saharae” Brit. Cactus and Succulent J. 17(3), 124-126.
[15] Bremer, K. (1994) Asteraceae: Cladistics and classification. Timber Press, Portland, Oregon.
[16] Wannes,W. A. and Marzouk, B. ( 2016) “Research progress of Tunisian medicinal plants used for acute diabetes” J. Acute Disease 5(5), 357–363
[17] Cox, P.A. and Balick M.J. (1994) “The ethnobotanical approach to drug discovery” Scientific American 270(6), 82–87.
[18] World Health Organization (WHO) (2000) General guidelines for methodologies on research and evaluation of traditional medicine, WHO, Geneva
[19] Cheriti, A., Rouissat, A., Sekkoum, K. and Balansard, G. (1995) "Plantes de la pharmacopée traditionelle dans la région d'El-Bayadh (Algérie)" Fitoterapia 66 (6), 525-538.
[20] Cheriti, A., Belboukhari, N. and Hacini, S. (2013). “ Ethnopharmacological survey and phytochemical screening of some medicinal Asteraceae from Algerian Sahara” Phytochem & BioSub J. 7 (2), 52-56.
[21] Cheriti, A. (2018). “Phytochemistry and biological activities of some endemic Saharan medicinal plants” Paper presented at the International Days of Organic Chemistry, Annaba, December 3-5.
[22] Watillon, C., Gaspar, T., Hofinger, M. and Ramaut, J.L. (1987) “La micropropagationde Warionia saharae Benth. & Coss.” Al Biruniya 4: 35-38.
[23] Berbaoui, H., Cheriti, A. and Ould El Hadj-Khelil, A. (2018) "Antibacterial Effect of Some Asteraceae of Southern Algeria on Nosocomial Strains of the Genus Staphylococcus" Nat Prod Chem Res 5: 302. doi:10.4172/2329-6836.1000302
[24] Rouissat, L. (2017). Etude des effets nématicides et molluscicides des extraits de quelques plantes sahariennes, Doctorat Diss., UAB-Oran 1
[25] Cheriti, A., Belboukhari, N., Bombarda, I. and Gaydou, E. (2010) “Antimicrobial Activity and Chemical Composition of the Essential Oil from the Sahara Endemic Medecinal Plant Warionia saharae (Asteraceae)” Rev. Regions Arides, 23(1), 103-107.
[26] (a) Belboukhari, M., Cheriti, A. and Belboukhri, N. (2011) “Total phenolic content and in vitro antioxydant activity of extracts from the endemic medicinal plant Warionia saharae” Nat. Prod.Ind. J., 7(3), 147-150. (b) Keffous, F., Belboukhari, N., Djeradi, H., N.M.Rebizi, Cheriti, A., Sekkoum, K. and Aboul-Enein, H. Y. (2019) “Optimization of the reducing power for antioxidant activity test and application on two medicinal plants” PhytoChem & BioSub J. 13(2), 81-85
[27] Znini, M., Cristofari, G., Majidi, L., El Harrak, A., Paolini, J. and Costa, J. (2013) “In vitro antifungal activity and chemical composition of Warionia saharae essential oil against 3 apple phytopathogenic fungi” Food Sci. Biotechnol. 22(S1), 113-119.
[28] Amezouar, F., Badri, W., Hsaine, M., Bourhim, N. and Fougrach, H. (2012) Chemical Composition, Antioxidant and Antibacterial Activities of Leaves Essential Oil and Ethanolic Extract of Moroccan Warionia saharae Benth. & Coss.” J. App. Pharm. Sci., 2(5), 212-217.
[29] Amezouar, F., Badri, W., Hsaine, M., Aksim M., Bourhim, N. and Fougrach, H.(2012) “subacute toxicity, anti-inflammatory and antioxidant activities of ethanolic extract of moroccan warionia saharae from Tata region” Intern. J. Pharm. Pharm. Sci. 4(5), 528-533.
[30] Mabry, T.J. and Bohlmann, F. (1977) Summary of the chemistry of the Compositae. In: Heywood, V.H . & al. (eds.), The Biology and Chemistry of the Compositae 2, Academic Press, London.
[31] Hilmi, F., Sticher, O. and Heilmann, J. (2002) “New Cytotoxic 6,7-cis and 6,7-trans configured Guaianolides from Warionia saharae” J. Nat. Prod.,65, 523-526.
[32] Hilmi, F., Gertsch, J., Bremner, P., Volovic, S., Heinrich, M., Sticher, O. and Heilmann, J. (2003) “Cytotoxic versus Anti-inflammatory effects in HeLa, Jurkat T and Human Peripheral Blood Cells caused by Guaianolide-Type sesquiterpene lactones” Bioorg. Med. Chem. 11, 3659-3663.
[33] Buckingham J., Cooper C. M. and Purchase R. (2016). Natural Products Desk Reference; CRC Taylor & francis, NY.
[34] Si-Yuan, P., Shu-Feng, Z., Si-Hua, G., Zhi-Ling, Y., Shuo-Feng, Z., Min-Ke, T., Jian-Ning, S., Dik-Lung, Ma.,Yi-Fan,H., Wang-Fun F. and Kam-Ming, K. (2013) “New Perspectives on How to Discover Drugs from Herbal Medicines: CAM’s Outstanding Contribution to Modern Therapeutics” Evidence-Based Complementary and Alternative Medicine, DOI: 10.1155/2013/627375
[35] Bucar, F., Wube A. and Schmid, M. (2013) “Natural product isolation – how to get from biological material to pure compounds” Nat. Prod. Rep. 30, 525–545.
[36] Sarker, S.D, Latif, Z. and Gray, A.I. (2005) Natural Products Isolation, 2ed Ed., Humana Press, New Jersey.
[37] Colegate, S. M. and Molyneux, R.J. (2007) Bioactive Natural Products: Detection, Isolation, and Structural Determination, Second Edition, 2ed Ed., CRC Press
[38] Ramaut, J. L., Hofimger, M., Dimbi, R., Corvisier, M. and Lewalle, J. (1985) “Main Constituents of the Essential Oil of Warionia Saharae Benth and Coss.” Chromatographia 20, 193-194.
[39] Yakoubi, M., Belboukhari, N., Sekkoum, K., Cheriti, A., Bouchekara, M.and Aboul-Enein, H. Y. (2015) “The Chemical Composition of Essential Oil of Warionea saharae Benth & Coss.(Fam.Asteraceae) from Southern Algeria” Current Bioactive Compounds, 11, 116-121
[40] Hilmi, F., Sticher, O. and Heilmann, J. (2003) “New cytotoxic sesquiterpene lactones from Warionia saharae. Planta Med. 69(5), 462-464.
[41] Essaqui, A., Elamrani, A., J. A. Cayuela and Benaissa, M. (2007) " Chemical Composition of the Essential Oil of Warionia saharae from Morocco” J. Ess. Oil Bear. Plants 10(3), 241 -246.
[42] Essaqui, A., Elamrani, A., Benaissa, M., Rodrigues, A. I. and Yoongho, L. (2004) " Chemical Composition of the leaves extract of Warionia saharae of Morocco” J. Ess. Oil Bear. Plants 7(3), 250-254,
[43] Sellam, K., Ramchoun, M., Alem, C., Khallouki, F., El Moualij, B. and El Rhaffari1, L. (2012) Chemical composition antioxidant and antimicrobial activities of essential oil of warionia saharae from oases of morocco, In: Gas Chromatography – Biochemicals, Narcotics and Essential Oils; Bekir Salih, Ömür Çelikb çak, Eds.; InTech, pp. 213-220.
[44] Mezhoud, S., Derbré, S., Ameddah, S., Mekkiou, R., Boumaza, O., Seghiri, R., Benayache, S., Richomme, P. and Benayache, F. (2012) “Antioxidant Activity And Chemical Constituents Of Warionia Saharae Benth. & Coss. (Compositae) From Algeria” Int. J. Med. Arom. Plants 2(3), 509-513.
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Published
2019-12-18
How to Cite
CHERITI, A.; DJERADI, H.; SEKKOUM, K.; BOUKHOBZA, Z. THE ENDEMIC MEDICINAL SPECIE WARIONIA SAHARAE ( ASTERACEAE): A PROMISING SOURCE OF BIOACTIVE NATURAL COMPOUNDS. Journal of Fundamental and Applied Sciences, [S. l.], v. 12, n. 1S, p. 141–157, 2019. DOI: 10.4314/jfas.v12i1S.11. Disponível em: https://jfas.info/index.php/JFAS/article/view/653. Acesso em: 30 jan. 2025.
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