INVESTIGATING THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF (PIMPINELLA ANISUM L.) ON HAIR GROWTH
DOI:
https://doi.org/10.4314/jfas.v11i2.5Keywords:
Pimpinella anisum L., Hair growth, mice, MinoxidilAbstract
In this study, the effects of above ground ethanol extracts (Pimpinella anisum L.) was assessed on hair growth. For this purpose, the prepared extract was treated as a positional solution on mice modified rear head area (dorsal) in 2%, 5%, 10% and 20% dosages. At the end of the 10th and 30th days, hair growth was assessed. The results showed significant differences between all the experimental groups and the control group (p<0.001). In 10% and 20% doses, there was Minoxidil effects. Based on these results, anise hydroalcohlic extract had a positive effect on the hair growth which is probably due to the effects of phytoestrogens in the plant.
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References
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[2] Lenane P, Macarthur C, Parkin PC, Krafchik B, DeGroot J, Khambalia A, Pope E. Clobetasol propionate, 0.05%, vs hydrocortisone, 1%, for alopecia areata in children: a randomized clinical trial. JAMA Dermatol. 2014 Jan;150(1):47-50.
[3] Tabanca N, Khan SI, Bedir E, Annavarapu S, Willett K, Khan IA, Kirimer N, Baser KH. Estrogenic activity of isolated compounds and essential oils of Pimpinella species from Turkey, evaluated using a recombinant yeast screen. Planta Med. 2004 Aug;70(8):728-35.
[4] Ingrid Herskovitz, Antonella Tosti. Female Pattern Hair Loss. Int J Endocrinol Metab. Oct 2013; 11(4): e9860.
[5] Hiradeve SM, Rangari VD. A review on pharmacology and toxicology of Elephantopus scaber Linn. Nat Prod Res. 2014;28(11):819-30.
[6] Venkateswara R G, Tiruganasambandham A, Triptikumar M. Phytochemical investigation and hair growth studies on the rhizomes of Nardostachys jatamansi DC. Pharmacogn Mag. 2011 Apr-Jun; 7(26): 146–150.
[7] Suphrom N, Srivilai J, Pumthong G, Khorana N, Waranuch N, Limpeanchob N, Ingkaninan K. Stability studies of antiandrogenic compounds in Curcuma aeruginosa Roxb. extract. J Pharm Pharmacol. 2014 Sep;66(9):1282-93.
[8] Randall VA, Botchkareva N. The Biology of Hair Growth. William Andrew Inc. Bradford, 2009.p.18-21
[9] Boldrin PK, Resende FA, Oliveira Höhne AP, Santoro de Camargo M, Espanha LG, Nogueira CH, Melo MF, Vilegas W, Varanda AV. Estrogenic and mutagenic activities of Crotalaria pallida measured by recombinant yeast assay and Ames test. BMC Complementary and Alternative Medicine 2013, 13:216-21
[10] Blume-Peytavi U, Kunte C, Krisp A, Garcia Bartels N, Ellwanger U, Hoffmann R. Comparison of the efficacy and safety of topical minoxidil and topical alfatradiol in the treatment of androgenetic alopecia in women. J Dtsch Dermatol Ges. 2007 May;5(5):391-5.
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Published
2019-04-01
How to Cite
MIRI, A.; SHAHRAKI, E. INVESTIGATING THE EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF (PIMPINELLA ANISUM L.) ON HAIR GROWTH. Journal of Fundamental and Applied Sciences, [S. l.], v. 11, n. 2, p. 623–631, 2019. DOI: 10.4314/jfas.v11i2.5. Disponível em: https://jfas.info/index.php/JFAS/article/view/49. Acesso em: 17 may. 2024.
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